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Sodium cromoglicate

CAS No. 15826-37-6

Sodium cromoglicate ( Cromolyn sodium;PA-101;FPL-670;Disodium cromoglicate )

Catalog No. M12261 CAS No. 15826-37-6

Sodium cromoglicate is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Sodium cromoglicate
  • Note
    Research use only, not for human use.
  • Brief Description
    Sodium cromoglicate is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells.
  • Description
    Sodium cromoglicate is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells; also inhibits chloride channels, and binds S100P to block the interaction between S100P and RAGE.Psoriasis Phase 3 Clinical
  • Synonyms
    Cromolyn sodium;PA-101;FPL-670;Disodium cromoglicate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PotassiumChannel;ProteinS100-P
  • Research Area
    Inflammation/Immunology
  • Indication
    Psoriasis

Chemical Information

  • CAS Number
    15826-37-6
  • Formula Weight
    512.33
  • Molecular Formula
    C23H14Na2O11
  • Purity
    >98% (HPLC)
  • Solubility
    water: 25.6 mg/mL (50 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    [Na+].OC(COC1=C2C(=O)C=C(OC2=CC=C1)C(O)=O)COC1=C2C(=O)C=C(OC2=CC=C1)C(O)=O
  • Chemical Name
    5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylic acid)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Heinke S, et al. Br J Pharmacol. 1995 Aug;115(8):1393-8.
2. Zur E, et al. Int J Pharm Compd. 2012 Sep-Oct;16(5):386-93.
3. Penumutchu SR, et al. Biochem Biophys Res Commun. 2014 Nov 21;454(3):404-9.
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